MediBalans · 13 Clinical Notes
Understand what symptoms and test results can mean. Explore explanations, clinical perspectives and the limits of research, with a direct link to each article.
HRV describes variation in the time between heartbeats. It can provide information about autonomic regulation of the heart, but a low value alone does not diagnose disease, nutrient deficiency or biological age.
Read the full article →How MediBalans uses a framework to prioritise clinical questions, with its evidence and limitations distinguished.
Read the full article →What a biological-age profile can estimate, why models differ and how results need interpretation.
Read the full article →IBS is a disorder of gut–brain interaction. Gut sensitivity, bowel movements, food and sometimes a previous intestinal infection can contribute. No single test identifies the cause in everyone with IBS.
Read the full article →Persistent fatigue has many possible causes. Stress-related exhaustion and ME/CFS are not the same condition. Assessment should consider the course of symptoms, how activity affects you and the results of previous investigations.
Read the full article →Autoimmune diseases involve immune responses against the body’s own tissues. They are a diverse group with different diagnostic and treatment pathways. Research on immune metabolism raises useful questions, but does not establish one shared cause or treatment for everyone.
Read the full article →We investigate what drives persistent fatigue, breathlessness, brain fog and other symptoms after COVID-19. Your history and previous findings help us prioritise targeted diagnostics and an individual plan for treatment and recovery.
Read the full article →Insulin resistance means that tissues including muscle, liver and fat respond less effectively to insulin. The body may compensate by producing more insulin, and blood glucose can rise over time. It is part of a complex metabolic process, not a diagnosis made from one symptom.
Read the full article →Senolytics are being studied for their effects on senescent cells. Polyphenols such as quercetin and fisetin feature in research, but that does not make supplements containing them an established treatment for ageing. A COMT variant does not provide a validated personalised dose.
Read the full article →NAD participates in cellular energy metabolism. Different precursor supplements are being studied, but higher NAD levels are not equivalent to demonstrated improvements in health or lifespan. Links with methylation need interpretation without treating biochemistry alone as clinical proof.
Read the full article →Evolutionary mismatch is a perspective on differences between today’s environment and conditions in which biological traits evolved. It is not a laboratory diagnosis. A test result needs assessment based on what the test measures and how well it has been validated.
Read the full article →Glutathione is part of the cell’s response to oxidative stress. Sulfur amino acids and one-carbon metabolism are biochemically connected, but that relationship does not automatically create a need for glutathione treatment or methyl-donor supplements.
Read the full article →Membrane order can help identify immune-cell states. A 2026 study offers a measurement for testing membrane-related GCR hypotheses; clinical uses remain unproven.
Read the full article →MediBalans + Meet Mario
For patients following a MediBalans protocol, Meet Mario can make the plan easier to follow between visits, with a meal plan, educational explanations and a separate channel to the care team.
See how Meet Mario supports your plan