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Precisionsmedicin · Regenerativ forskning · Patentportfölj

Forskning som
förändrar kliniken

MediBalans conducts clinical research with direct application in patient care. Our work on Global Constraint Rule, biological age measurement and regenerative therapies is translated into protocols used at the clinic today — inte om tio år.

7 Patent
3 Research Domains
42K Biomarkörer (BioAge™)
Unifying Principle

Global Constraint Rule

The scientific foundation unifying MediBalans patent portfolio and clinical methodology.

Global Constraint Rule (GCR) is a systems biology principle describing how biological systems — from individual cells to entire organs — always operate under prevailing constraints. När en begränsning är tillräckligt allvarlig, omkonfigureras hela systemet för att kompensera.

The clinical problem is that the visible dysfunction is rarely the primary constraint. Conventional medicine often treats the secondary compensation — and wonders why the effect is absent or recurs.

The GCR framework guides MediBalans diagnostics: we systematically search for the biological root constraint driving a condition, regardless of where it manifests clinically. This is the principle behind why the same symptom can require entirely different treatment in different patients.

Seven patents have so far emerged from this framework — in longevity medicine, regenerative therapies and precision nutrition.

Global Constraint Rule · Core Definition

Biological systems always adapt to their most limiting factor — not their most obvious one.

Identifying and correcting the root constraint is more effective than treating the adaptive compensations it has generated.

The same symptom can have fundamentally different biological origins
Treating compensations gives temporary effect — treating the constraint gives lasting results
Multi-omics diagnostics can identify the constraint with high precision
Protocol design must be adapted to the individual's specific constraint profile
Intellectual Property

7 Patent inom precisionsmedicin

The patent portfolio spans longevity medicine, regenerative therapies and precision nutrition — all unified by the Global Constraint Rule principle.

Patent 01 · Longevity
Biological Age Determination via RNA Transcriptome Analysis
Method for measuring biological age at cellular level through gene expression profiling against validated longevity biomarkers.
MediBalans BioAge™
Patent 02 · Regenerativ
Translational Gap Analysis for Proteomic Intervention
Patented method for identifying the discrepancy between gene expression and protein production — the translational gap driving cellular dysfunction.
Proteomik
Patent 03 · Precision Nutrition
Intracellular Micronutrient Mapping for Protocol Design
System for translating intracellular nutritional status (42 micronutrients) into personalised supplementation protocols via GCR ranking.
CMA · Nutrition
Patent 04 · Immunologi
Dynamic Immune Reactivity Profile for Elimination Protocols
Method for time-series measurement of immune reactivity to food antigens and translating change patterns into adaptive elimination and reintroduction protocols.
ALCAT · Immunologi
Patent 05 · Metylering
Methylation Capacity Index for Regenerative Treatment Planning
Algorithm integrating SNP profile, biomarker data and clinical anamnesis into a composite methylation capacity index with direct protocol implications.
MethylDetox · Epigenetik
Patent 06 · Neurologi
Autonomic Regulation via HRV Biofeedback and Cellular Nutrition
Combination protocol integrating HRV measurement with cellular nutritional status to optimise autonomic nerve regulation and mitochondrial function.
HRV · Mitokondrier
Patent 07 · Regenerativ
Multi-Omics Convergence Model for Systems Biology Diagnosis
Framework for integrating genomics, transcriptomics, proteomics and metabolomics into a convergent biological constraint profile in accordance with GCR.
Multi-omics · GCR
Patented Formulation · Longevity
NMN+5™
Standard NMN raises NAD+ but depletes methyl groups — creating risk of homocysteine accumulation. NMN+5™ combines NMN with five synergistic cofactors (TMG, L-5-methylfolate, P5P, R5P, hydroxy/adenosyl-B12) to sustain methylation integrity simultaneously. NAD+ provides power. Methylation provides control. NMN+5™ provides both.
Cofactors
Trimethylglycine (TMG)
L-5-Methylfolate (B9)
Pyridoxal-5-phosphate (B6)
Riboflavin-5-phosphate (B2)
Hydroxy/Adenosyl-B12
Patent-protected formulation
Flagship

MediBalans BioAge™

Our most advanced diagnostic product — a multi-layer measurement of biological age at cellular, genetic and proteomic level.

Chronological age tells you nothing about how your body is actually ageing. MediBalans BioAge™ measures biological age on three levels: RNA-transkriptomanalys (42 000 biomarkörer), proteomisk profil och patenterad translationell gap-analys.

Resultatet är ett biologiskt ålderstal med specificerade avvikelsemönster — and a treatment plan designed to reduce the biological processes driving premature cellular ageing.

The test is performed in partnership with Dante Labs and their RNA transcriptome analysis platform. Clinical interpretation and protocol design is performed by Dr Mario Anthis personally.

Book BioAge™ Investigation →
01
RNA-Transkriptomanalys
42 000 biomarkörer för genexpression och longevity-profil
Dante Labs
02
Proteomisk Analys
Proteinproduktionsprofil mot longevity-referenspanel
Proteomik
03
Translational Gap Analysis
Patented method for measuring gene→protein discrepancy
Patenterad
04
GCR Åldringsprofil
Identification of primary biological ageing vector per GCR
GCR
05
Kliniskt Protokoll
Personalised plan for biological age reduction
Behandling
Jag var 48 och ville veta hur min kropp faktiskt åldrades — inte vad mitt pass säger. BioAge-testet gav mig ett biologiskt ålderstal och en konkret plan. Tre månader senare hade jag mätbara förbättringar på alla markörer.
Stefan W.  ★★★★★
BioAge™ · Longevity
Verified on Reco.se →
Partnerships

Kliniska samarbeten

MediBalans collaborates with leading diagnostic laboratories to ensure our diagnostics maintain scientific excellence.

Dante Labs
Multi-omics · Genomik · Transkriptomik
Official partnership for RNA transcriptome analysis and whole genome sequencing. Dante Labs' platform powers MediBalans BioAge™ at laboratory level — 42,000 biomarkers analysed according to validated longevity protocol.
RNA-transkriptomanalys (42 000 markörer)
Whole Genome Sequencing WGS 30x
Proteomic analysis
Genova Diagnostics
Funktionell diagnostik · Officiell distributör
MediBalans is the official distributor of Genova Diagnostics in Sweden. Genova is a world-leading provider of functional diagnostic tests in gut health, hormones, nutritional status and metabolomics.
GI Effects® Comprehensive Stool Profile
DUTCH Complete hormonpanel
NutrEval® metabolomik
Cell Science Systems
Immunreaktivitet · Officiell distributör
Official distributor of the ALCAT test in Sweden. Cell Science Systems are the creators of ALCAT — the most validated test for delayed immune reactivity to foods, additives and chemicals.
ALCAT 200+ livsmedel
ALCAT kemikalier & tillsatser
ALCAT mögel & antibiotika
Spectracell Laboratories
Intracellulär näring · CMA
Provider of Comprehensive Micronutrient Analysis (CMA) — the world's most validated test for intracellular nutritional status. Measures 42 micronutrients directly in white blood cells to reveal true cellular nutritional status.
CMA — 42 intracellulära mikronäringsämnen
Antioxidant status and immune function
Applied Research

Forskning som används på dig

Our research is not academic — it is applied directly in every patient encounter. Book a consultation to see how the GCR framework and our diagnostic portfolio can be applied to your situation.

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